|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
solute carrier family 5 member 2
|
|
gptkbp:associatedWith
|
familial renal glucosuria
|
|
gptkbp:discoveredIn
|
1994
|
|
gptkbp:encodes
|
Sodium/glucose cotransporter 2
|
|
gptkbp:Entrez_Gene_ID
|
6524
ENSG00000100170
|
|
gptkbp:expressedIn
|
gptkb:kidney
|
|
gptkbp:function
|
glucose reabsorption in proximal tubule
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
NM_003041
|
|
gptkbp:HGNC_ID
|
11052
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SLC5A2
|
|
gptkbp:inhibitorDrug
|
gptkb:dapagliflozin
gptkb:empagliflozin
gptkb:canagliflozin
gptkb:ertugliflozin
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_16
|
|
gptkbp:mutationAssociatedWith
|
renal glucosuria
|
|
gptkbp:OMIM
|
600457
|
|
gptkbp:orthologInMouse
|
Slc5a2
|
|
gptkbp:product
|
gptkb:SGLT2
|
|
gptkbp:proteinFamily
|
gptkb:solute_carrier_family
|
|
gptkbp:publicTransit
|
sodium-glucose symporter
|
|
gptkbp:significance
|
type 2 diabetes treatment
|
|
gptkbp:target
|
gptkb:SGLT2_inhibitors
|
|
gptkbp:UniProtID
|
P31639
|
|
gptkbp:bfsParent
|
gptkb:solute_carrier_family
|
|
gptkbp:bfsLayer
|
6
|