|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
Na+/glucose cotransporter 1
solute carrier family 5 member 1
|
|
gptkbp:associatedWith
|
glucose absorption
glucose-galactose malabsorption
|
|
gptkbp:discoveredBy
|
Ernest M. Wright
|
|
gptkbp:discoveredIn
|
1987
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gptkbp:encodedBy
|
SLC5A1 gene
|
|
gptkbp:expressedIn
|
enterocytes
proximal tubule cells
|
|
gptkbp:foundIn
|
gptkb:kidney
gptkb:small_intestine
|
|
gptkbp:fullName
|
Sodium/glucose cotransporter 1
|
|
gptkbp:function
|
transports glucose and galactose across cell membranes
|
|
gptkbp:gene
|
SLC5A1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SGLT1
|
|
gptkbp:inhibitedBy
|
phlorizin
|
|
gptkbp:locatedOnChromosome
|
chromosome 22q12.3
|
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gptkbp:mechanismOfAction
|
sodium-dependent glucose transport
|
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gptkbp:molecularWeight
|
73 kDa
|
|
gptkbp:orthologIn
|
gptkb:zebrafish
right
|
|
gptkbp:significance
|
mutations cause glucose-galactose malabsorption
|
|
gptkbp:structureType
|
integral membrane protein
|
|
gptkbp:transmembraneDomains
|
14
|
|
gptkbp:transportation
|
glucose
galactose
|
|
gptkbp:transportsWith
|
sodium ions
|
|
gptkbp:UniProtID
|
P13866
|
|
gptkbp:bfsParent
|
gptkb:SGLT
|
|
gptkbp:bfsLayer
|
7
|