Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:alsoKnownAs |
NSC 74859
|
| gptkbp:application |
preclinical studies
|
| gptkbp:CASNumber |
501919-59-1
|
| gptkbp:category |
small molecule
|
| gptkbp:chemicalFormula |
C18H13N3O2S
|
| gptkbp:discoveredBy |
City of Hope researchers
|
| gptkbp:effect |
inhibits tumor cell growth
|
| gptkbp:function |
STAT3 inhibitor
|
| https://www.w3.org/2000/01/rdf-schema#label |
S3I-201
|
| gptkbp:mechanismOfAction |
blocks STAT3 dimerization
|
| gptkbp:molecularWeight |
335.38 g/mol
|
| gptkbp:structureContains |
sulfonamide group
indole group |
| gptkbp:target |
gptkb:STAT3
|
| gptkbp:usedIn |
cancer research
|
| gptkbp:bfsParent |
gptkb:STAT3
|
| gptkbp:bfsLayer |
7
|