Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
gptkb:coenzyme |
| gptkbp:biosynthesized_from |
gptkb:ATP
methionine |
| gptkbp:CASNumber |
29908-03-0
|
| gptkbp:category |
nucleosides
coenzymes amino acid derivatives sulfonium compounds |
| gptkbp:chemicalFormula |
C15H22N6O5S
|
| gptkbp:chirality |
S-enantiomer
|
| gptkbp:decarboxylatedBy |
S-adenosylmethionine decarboxylase
|
| gptkbp:degradedBy |
S-adenosylhomocysteine hydrolase
|
| gptkbp:discoveredBy |
gptkb:Giulio_Cantoni
|
| gptkbp:discoveredIn |
1952
|
| gptkbp:foundIn |
all living cells
|
| gptkbp:function |
aminopropylation
transmethylation transsulfuration methylation reactions |
| gptkbp:hasInChIKey |
MEFKEPWMEQBLKI-BTVCUQKSSA-N
|
| https://www.w3.org/2000/01/rdf-schema#label |
S-adenosylmethionine
|
| gptkbp:IUPACName |
(2S)-2-amino-4-[[2-[(1,2-dihydroxyethyl)methylsulfonio]ethyl]amino]-4-oxobutanoic acid
|
| gptkbp:KEGGID |
C00019
|
| gptkbp:meltingPoint |
>200°C (decomposes)
|
| gptkbp:MeSH_ID |
D012446
|
| gptkbp:molecularWeight |
398.44 g/mol
|
| gptkbp:otherName |
gptkb:AdoMet
gptkb:SAM gptkb:SAME |
| gptkbp:predecessor |
polyamines
homocysteine 5-methyltetrahydrofolate |
| gptkbp:producedByEnzyme |
gptkb:methionine_adenosyltransferase
|
| gptkbp:PubChem_CID |
gptkb:DB00118
gptkb:CHEMBL418 34755 CHEBI:16810 |
| gptkbp:role |
methyl group donor
precursor in biosynthesis |
| gptkbp:sideEffect |
anxiety
insomnia gastrointestinal upset |
| gptkbp:solubility |
gptkb:water
|
| gptkbp:UNII |
Q9Q0K6Q1J1
|
| gptkbp:usedIn |
treatment of depression
treatment of liver disease treatment of osteoarthritis |
| gptkbp:bfsParent |
gptkb:C00243
|
| gptkbp:bfsLayer |
6
|