Sézary syndrome

GPTKB entity

Statements (37)
Predicate Object
gptkbp:instanceOf gptkb:leukemia
gptkb:disease
gptkbp:affects gptkb:skin
blood
lymph nodes
gptkbp:affectsDemographic older adults
gptkbp:associatedWith chromosome 17q11-q12
gptkbp:causedBy malignant proliferation of T-cells
gptkbp:differentialDiagnosis gptkb:eczema
gptkb:atopic_dermatitis
psoriasis
gptkbp:firstDescribed 1938
gptkbp:hasDiagnosticMethod blood smear
skin biopsy
flow cytometry
gptkbp:hasType CD4+ T-cells
Sézary cells
gptkbp:ICD-10_code C84.1
gptkbp:MeSH_ID D012704
gptkbp:mortalityRate high
gptkbp:namedAfter Albert Sézary
gptkbp:OMIM 254400
gptkbp:prevalence rare
gptkbp:prognosis poor
gptkbp:subspecies gptkb:mycosis_fungoides
gptkbp:symptom pruritus
lymphadenopathy
erythroderma
presence of Sézary cells in blood
gptkbp:treatment gptkb:immunotherapy
chemotherapy
stem cell transplant
retinoids
photopheresis
gptkbp:bfsParent gptkb:Mycosis_fungoides
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label Sézary syndrome

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