Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
gptkb:monoclonal_antibody |
| gptkbp:announced |
2015
|
| gptkbp:chemicalClass |
monoclonal antibody conjugated to cytotoxic agent
|
| gptkbp:clinicalTrialPhase |
Phase III
|
| gptkbp:developedBy |
gptkb:AbbVie
gptkb:Stemcentrx |
| gptkbp:discontinued |
lack of efficacy
|
| https://www.w3.org/2000/01/rdf-schema#label |
Rova-T
|
| gptkbp:indication |
Small Cell Lung Cancer
|
| gptkbp:macromoleculeType |
gptkb:delta-like_protein_3
|
| gptkbp:mechanismOfAction |
targets and binds to DLL3 protein on cancer cells
|
| gptkbp:otherName |
gptkb:rovalpituzumab_tesirine
SC16LD6.5 |
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
serious adverse events in clinical trials
|
| gptkbp:status |
development discontinued
|
| gptkbp:target |
gptkb:DLL3
|
| gptkbp:bfsParent |
gptkb:Stemcentrx
|
| gptkbp:bfsLayer |
7
|