|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:abusePotential
|
high
yes
|
|
gptkbp:approvedBy
|
gptkb:Australia
gptkb:Canada
gptkb:United_Kingdom
gptkb:United_States
1955
|
|
gptkbp:ATCCode
|
N06BA04
|
|
gptkbp:brand
|
gptkb:Ritalin
gptkb:Concerta
gptkb:Methylin
Metadate
|
|
gptkbp:chemicalFormula
|
C14H19NO2
|
|
gptkbp:contraindication
|
anxiety
glaucoma
Tourette syndrome
tics
|
|
gptkbp:controlledSubstanceSchedule
|
gptkb:Schedule_II_(US)
|
|
gptkbp:discoveredBy
|
gptkb:Leandro_Panizzon
|
|
gptkbp:drugClass
|
stimulant
|
|
gptkbp:eliminationHalfLife
|
2-3 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:form
|
gptkb:tablet
extended-release tablet
|
|
gptkbp:genericName
|
gptkb:methylphenidate
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ritalin
|
|
gptkbp:interactsWith
|
gptkb:monoamine_oxidase_inhibitors
anticonvulsants
antidepressants
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:manufacturer
|
gptkb:Novartis
|
|
gptkbp:mechanismOfAction
|
norepinephrine reuptake inhibitor
dopamine reuptake inhibitor
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:overdoseSymptoms
|
vomiting
agitation
tremors
convulsions
|
|
gptkbp:patent
|
1954
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:prescribes
|
adolescents
adults
children
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
loss of appetite
increased heart rate
nervousness
insomnia
|
|
gptkbp:usedFor
|
gptkb:attention_deficit_hyperactivity_disorder
narcolepsy
|
|
gptkbp:bfsParent
|
gptkb:Novartis
|
|
gptkbp:bfsLayer
|
4
|