|
gptkbp:instanceOf
|
gptkb:Dragon
gptkb:protein
|
|
gptkbp:A_chain_function
|
enzymatic activity
|
|
gptkbp:antidote
|
none
|
|
gptkbp:B_chain_function
|
binds to cell surface
|
|
gptkbp:CASNumber
|
9009-86-3
|
|
gptkbp:category
|
plant toxin
biotoxin
ribosome-inactivating protein
|
|
gptkbp:discoveredBy
|
Peter Hermann Stillmark
|
|
gptkbp:discoveredIn
|
1888
|
|
gptkbp:foundIn
|
castor beans
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ricin toxin
|
|
gptkbp:LD50
|
~1-2 mg for adult human (injected or inhaled)
|
|
gptkbp:mechanismOfAction
|
inhibits protein synthesis
|
|
gptkbp:molecularWeight
|
~65 kDa
|
|
gptkbp:notableEvent
|
assassination of Georgi Markov
|
|
gptkbp:producedBy
|
Ricinus communis
|
|
gptkbp:PubChem_CID
|
16129788
|
|
gptkbp:regulates
|
gptkb:Centers_for_Disease_Control_and_Prevention
gptkb:Chemical_Weapons_Convention
|
|
gptkbp:riskFactor
|
extremely toxic
|
|
gptkbp:routeOfExposure
|
injection
inhalation
ingestion
|
|
gptkbp:solubility
|
water-soluble
|
|
gptkbp:stable
|
inactivated by heat above 80°C
|
|
gptkbp:structure
|
A and B chains
|
|
gptkbp:symptom
|
death
nausea
vomiting
diarrhea
organ failure
|
|
gptkbp:UNII
|
W9A7U6M3MP
|
|
gptkbp:uses
|
biological warfare
|
|
gptkbp:bfsParent
|
gptkb:USAMRIID
|
|
gptkbp:bfsLayer
|
7
|