Statements (95)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DJ
|
| gptkbp:bfsLayer |
7
|
| gptkbp:bfsParent |
gptkb:WAVE_complex
gptkb:mi_R-145 |
| gptkbp:established |
Rho GA Ps
guanine nucleotide exchange factors (GE Fs) |
| gptkbp:function |
regulates the cytoskeleton
|
| gptkbp:has_role |
gptkb:psychologist
tumor progression |
| https://www.w3.org/2000/01/rdf-schema#label |
Rho A
|
| gptkbp:interacts_with |
gptkb:LIM-kinase
gptkb:Rho-kinase m Dia p160 ROCK |
| gptkbp:is_involved_in |
apoptosis
cell cycle regulation cell differentiation cell shape maintenance immune response muscle contraction signal transduction inflammation wound healing fibrosis cardiovascular diseases neuronal signaling extracellular matrix remodeling angiogenesis cell adhesion cell migration metastasis neurite outgrowth smooth muscle contraction cellular response to DNA damage endothelial barrier function cellular response to bacterial infection cellular response to cytokines cellular response to fungal infection cellular response to hormones cellular response to mechanical stress cellular response to oxidative stress cellular response to parasitic infection cellular response to temperature changes cellular response to viral infection cellular response to radiation cellular response to aging cellular response to apoptosis signals cellular response to drugs cellular response to environmental changes cellular response to growth factors cellular response to toxins cellular response to allergens cellular response to nutrient availability cellular response to radiation exposure stress fiber formation cellular response to autocrine signals cellular response to autophagy signals cellular response to circadian signals cellular response to differentiation signals cellular response to endocrine signals cellular response to environmental signals cellular response to growth signals cellular response to metabolic signals cellular response to neuroendocrine signals cellular response to paracrine signals cellular response to stress signals cellular response to death signals cellular response to survival signals cell polarity cellular response to cultural signals cellular response to economic signals cellular response to heavy metals cellular response to homeostasis signals cellular response to inflammation signals cellular response to necrosis signals cellular response to p H changes cellular response to pathogens cellular response to political signals cellular response to pollutants cellular response to regeneration signals cellular response to repair signals cellular response to seasonal signals cellular response to senescence cellular response to social signals cellular response to stressors cellular response to technological signals focal adhesion formation |
| gptkbp:is_represented_in |
various tissues
|
| gptkbp:located_in |
cytoplasm
plasma membrane |
| gptkbp:part_of |
Rho family of GT Pases
|
| gptkbp:promoter |
RHOA
|
| gptkbp:regulates |
gene expression
actin polymerization |
| gptkbp:weight |
21 k Da
|