Statements (56)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:activities |
gptkb:fragrance
inhibits dihydrofolate reductase |
| gptkbp:approves |
1953
|
| gptkbp:brand |
gptkb:Trexall
gptkb:Otrexup gptkb:Rasuvo |
| gptkbp:category |
gptkb:X
not recommended |
| gptkbp:contraindication |
alcohol consumption
pregnancy breastfeeding |
| gptkbp:dosage_form |
injection
oral tablet |
| gptkbp:education |
avoid alcohol
stay hydrated avoid live vaccines report signs of infection |
| gptkbp:excretion |
urine
|
| gptkbp:formulation |
gptkb:tablet
injection solution |
| https://www.w3.org/2000/01/rdf-schema#label |
Rheumatrex
|
| gptkbp:indication |
gptkb:healthcare_organization
gptkb:non-Hodgkin_lymphoma gptkb:choriocarcinoma gestational trophoblastic disease severe psoriasis |
| gptkbp:ingredients |
gptkb:methotrexate
C20 H22 N8 O5 |
| gptkbp:interacts_with |
live vaccines
penicillins NSAI Ds sulfonamides |
| gptkbp:is_atype_of |
L01 B A01
|
| gptkbp:is_monitored_by |
liver function tests
complete blood count renal function tests |
| gptkbp:is_used_for |
treatment of psoriasis
treatment of rheumatoid arthritis treatment of certain types of cancer |
| gptkbp:legal_issue |
prescription only
|
| gptkbp:lifespan |
3 to 10 hours
|
| gptkbp:manager |
oral
injection |
| gptkbp:manufacturer |
various pharmaceutical companies
|
| gptkbp:metabolism |
hepatic
|
| gptkbp:rounds |
renal
|
| gptkbp:side_effect |
fatigue
nausea liver toxicity mouth sores |
| gptkbp:storage |
room temperature
protected from light |
| gptkbp:type_of |
59-05-2
|
| gptkbp:bfsParent |
gptkb:methotrexate
|
| gptkbp:bfsLayer |
4
|