Restless legs syndrome

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf neurological disorder
gptkbp:abbreviation gptkb:RLS
gptkbp:affects gptkb:nervous_system
gptkbp:alsoKnownAs gptkb:Willis-Ekbom_disease
gptkbp:category movement disorder
Sleep disorder
gptkbp:cause unknown
gptkbp:complication gptkb:depression
sleep disturbance
daytime fatigue
gptkbp:diagnosedBy clinical evaluation
sleep study (in some cases)
gptkbp:firstDescribed gptkb:Thomas_Willis
1672
gptkbp:hasNoCure true
https://www.w3.org/2000/01/rdf-schema#label Restless legs syndrome
gptkbp:ICD-10_code G25.81
gptkbp:improves exercise
massage
stretching
hot or cold packs
gptkbp:MeSH_ID D020754
gptkbp:namedAfter gptkb:Karl-Axel_Ekbom
gptkbp:OMIM 102300
gptkbp:prevalence more common in women
2-10% of adults
gptkbp:relatedTo gptkb:periodic_limb_movement_disorder
gptkbp:riskFactor family history
certain medications
pregnancy
chronic kidney disease
iron deficiency
gptkbp:symptom relief with movement
uncomfortable sensations in the legs
urge to move the legs
worse in the evening or night
worsening of symptoms at rest
gptkbp:treatment gptkb:gabapentin
gptkb:pregabalin
dopamine agonists
lifestyle changes
iron supplements
opioids (in severe cases)
gptkbp:worsenedBy gptkb:beer
caffeine
antipsychotics
antihistamines
antidepressants
gptkbp:bfsParent gptkb:Insomnia
gptkbp:bfsLayer 5