| 
                                    
                                        gptkbp:instanceOf
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:neurological_disorder
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:abbreviation
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:RLS
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:affects
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:nervous_system
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:alsoKnownAs
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Willis-Ekbom_disease
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:category
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:movement_disorder
                                        
                                         
                                    
                                        
                                            gptkb:Sleep_disorder
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:cause
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:unknown
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:complication
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:depression
                                        
                                         
                                    
                                        
                                            
                                            sleep disturbance
                                        
                                        
                                         
                                    
                                        
                                            
                                            daytime fatigue
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:diagnosedBy
                                    
                                 | 
                                
                                    
                                        
                                            
                                            clinical evaluation
                                        
                                        
                                         
                                    
                                        
                                            
                                            sleep study (in some cases)
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:firstDescribed
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Thomas_Willis
                                        
                                         
                                    
                                        
                                            
                                            1672
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:hasNoCure
                                    
                                 | 
                                
                                    
                                        
                                            
                                            true
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:ICD-10_code
                                    
                                 | 
                                
                                    
                                        
                                            
                                            G25.81
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:improves
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:exercise
                                        
                                         
                                    
                                        
                                            
                                            massage
                                        
                                        
                                         
                                    
                                        
                                            
                                            stretching
                                        
                                        
                                         
                                    
                                        
                                            
                                            hot or cold packs
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:MeSH_ID
                                    
                                 | 
                                
                                    
                                        
                                            
                                            D020754
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:namedAfter
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Karl-Axel_Ekbom
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:OMIM
                                    
                                 | 
                                
                                    
                                        
                                            
                                            102300
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:prevalence
                                    
                                 | 
                                
                                    
                                        
                                            
                                            more common in women
                                        
                                        
                                         
                                    
                                        
                                            
                                            2-10% of adults
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:relatedTo
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:periodic_limb_movement_disorder
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:riskFactor
                                    
                                 | 
                                
                                    
                                        
                                            
                                            family history
                                        
                                        
                                         
                                    
                                        
                                            
                                            certain medications
                                        
                                        
                                         
                                    
                                        
                                            
                                            pregnancy
                                        
                                        
                                         
                                    
                                        
                                            
                                            chronic kidney disease
                                        
                                        
                                         
                                    
                                        
                                            
                                            iron deficiency
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:symptom
                                    
                                 | 
                                
                                    
                                        
                                            
                                            relief with movement
                                        
                                        
                                         
                                    
                                        
                                            
                                            uncomfortable sensations in the legs
                                        
                                        
                                         
                                    
                                        
                                            
                                            urge to move the legs
                                        
                                        
                                         
                                    
                                        
                                            
                                            worse in the evening or night
                                        
                                        
                                         
                                    
                                        
                                            
                                            worsening of symptoms at rest
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:treatment
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:gabapentin
                                        
                                         
                                    
                                        
                                            gptkb:pregabalin
                                        
                                         
                                    
                                        
                                            
                                            dopamine agonists
                                        
                                        
                                         
                                    
                                        
                                            
                                            lifestyle changes
                                        
                                        
                                         
                                    
                                        
                                            
                                            iron supplements
                                        
                                        
                                         
                                    
                                        
                                            
                                            opioids (in severe cases)
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:worsenedBy
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:beer
                                        
                                         
                                    
                                        
                                            
                                            caffeine
                                        
                                        
                                         
                                    
                                        
                                            
                                            antipsychotics
                                        
                                        
                                         
                                    
                                        
                                            
                                            antihistamines
                                        
                                        
                                         
                                    
                                        
                                            
                                            antidepressants
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsParent
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Insomnia
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsLayer
                                    
                                 | 
                                
                                    
                                        
                                            
                                            5
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        https://www.w3.org/2000/01/rdf-schema#label
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Restless legs syndrome
                                        
                                        
                                         
                                    
                                 |