Relaxin (serelaxin)

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:drug
hormone
gptkbp:administeredBy intravenous infusion
gptkbp:approvedBy gptkb:Russia
gptkbp:ATCCode H01AX27
gptkbp:brand Reasanz
gptkbp:CASNumber 161481-09-6
gptkbp:clinicalTrialPhase Phase III
gptkbp:compatibleWith gptkb:European_Union
gptkb:United_States
gptkbp:developedBy gptkb:Novartis
gptkbp:hasClinicalTrialName RELAX-AHF
RELAX-AHF-2
gptkbp:hasMolecularFormula C256H408N74O76S6
https://www.w3.org/2000/01/rdf-schema#label Relaxin (serelaxin)
gptkbp:isPeptide true
gptkbp:isRecombinantFormOf human relaxin-2
gptkbp:mechanismOfAction vasodilation
increases renal blood flow
reduces systemic vascular resistance
gptkbp:molecularWeight 5987 Da
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect nausea
dizziness
headache
hypotension
gptkbp:targetsReceptor relaxin family peptide receptor 1 (RXFP1)
gptkbp:UNII 6Z5B6HVF6O
gptkbp:usedFor acute heart failure
gptkbp:bfsParent gptkb:Corthera
gptkbp:bfsLayer 7