Reductive amination

GPTKB entity

Statements (20)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkbp:alsoKnownAs reductive alkylation
gptkbp:category gptkb:chemical_compound
reduction reaction
amine synthesis
gptkbp:commonReagents hydrogen and catalyst
sodium cyanoborohydride
sodium triacetoxyborohydride
https://www.w3.org/2000/01/rdf-schema#label Reductive amination
gptkbp:involves conversion of a carbonyl group to an amine
reaction of an aldehyde or ketone with an amine
reduction step
gptkbp:mechanismOfAction formation of imine or iminium ion intermediate
reduction of imine or iminium ion
gptkbp:product amphetamine
gptkbp:usedIn organic synthesis
pharmaceutical synthesis
synthesis of alkylamines
gptkbp:bfsParent gptkb:Amines
gptkbp:bfsLayer 8