Statements (26)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:virus
|
gptkbp:antigen |
site II
site IV site V site VIII site Ø |
gptkbp:contains |
fusion peptide
|
gptkbp:existsIn |
post-fusion conformation
pre-fusion conformation |
gptkbp:expressedIn |
infected host cells
|
gptkbp:foundIn |
gptkb:respiratory_syncytial_virus
|
gptkbp:function |
mediates fusion of viral and host cell membranes
|
gptkbp:gene |
F gene
|
gptkbp:glycosylation |
yes
|
https://www.w3.org/2000/01/rdf-schema#label |
RSV F protein
|
gptkbp:importantFor |
viral entry
syncytium formation |
gptkbp:molecularWeight |
~70 kDa
|
gptkbp:recognizedBy |
neutralizing antibodies
|
gptkbp:structure |
trimeric
|
gptkbp:target |
gptkb:palivizumab
gptkb:nirsevimab |
gptkbp:usedFor |
serological diagnosis of RSV infection
|
gptkbp:usedIn |
RSV vaccine development
|
gptkbp:bfsParent |
gptkb:palivizumab
|
gptkbp:bfsLayer |
7
|