Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:bfsLayer |
2
|
| gptkbp:bfsParent |
gptkb:physicist
|
| gptkbp:activities |
transcription of r RNA genes
|
| gptkbp:difficulty |
multi-subunit enzyme
|
| gptkbp:discovered_by |
discovered in the 1960s
|
| gptkbp:established |
gptkb:actinomycin_D
|
| gptkbp:function |
synthesizes ribosomal RNA (r RNA)
|
| gptkbp:has_member |
largest subunit (A190)
second largest subunit (A135) |
| https://www.w3.org/2000/01/rdf-schema#label |
RNA Polymerase I
|
| gptkbp:interacts_with |
interacts with selectivity factor 1 (S L1)
interacts with upstream binding factor (UBF) |
| gptkbp:is_essential_for |
critical for cell growth and proliferation
|
| gptkbp:is_similar_to |
similar to RNA Polymerase III
|
| gptkbp:location |
nucleolus
|
| gptkbp:origin |
evolved from a common ancestor with other polymerases
|
| gptkbp:products |
pre-r RNA
|
| gptkbp:regulatory_compliance |
controlled by transcription factors
|
| gptkbp:responsible_for |
synthesizing r RNA
|
| gptkbp:role |
essential for ribosome biogenesis
|
| gptkbp:services |
involves specific termination signals
|
| gptkbp:social_responsibility |
linked to certain cancers
|
| gptkbp:species |
found in eukaryotes
|
| gptkbp:transcribed_for |
requires specific promoter elements
|
| gptkbp:transponders |
r RNA genes
|