Primary lateral sclerosis

GPTKB entity

Statements (61)
Predicate Object
gptkbp:instance_of gptkb:disease
gptkbp:advocacy necessary
gptkbp:affects motor neurons
gptkbp:caregiver_support important
gptkbp:clinical_trial available
upper motor neuron signs
no lower motor neuron involvement
gptkbp:community_impact gptkb:significant
gptkbp:community_support important
gptkbp:condition gptkb:amyotrophic_lateral_sclerosis
gptkb:multiple_sclerosis
gptkbp:diagnosis clinical evaluation
MRI scan
electromyography
El Escorial criteria
important to rule out other conditions
gptkbp:diagnosis_age_range 30 to 60 years
gptkbp:educational_resources important for patients and families
gptkbp:financial_support essential
gptkbp:funding limited
gptkbp:gender more common in men
gptkbp:genetic_studies not well understood
https://www.w3.org/2000/01/rdf-schema#label Primary lateral sclerosis
gptkbp:impact_on_daily_life gptkb:significant
gptkbp:investigates lack of awareness
limited patient population
gptkbp:is_a_resource_for support groups
gptkbp:is_involved_in gptkb:ALS_Association
gptkb:MDA_(Muscular_Dystrophy_Association)
gptkbp:lifespan varies by individual
gptkbp:long-term_care often required
gptkbp:muscle_atrophy not common
gptkbp:neurological_examination important for diagnosis
gptkbp:patient_population available online
gptkbp:player_development slow
gptkbp:premiered_on adulthood
gptkbp:prevalence rare
gptkbp:public_awareness increasing
gptkbp:research ongoing
gptkbp:research_focus understanding pathophysiology
developing treatments
gptkbp:symptoms fatigue
medications
muscle weakness
muscle stiffness
assistive devices
gradual
muscle cramps
emotional changes
cognitive changes
twitching
spasticity
difficulty with speech
difficulty with swallowing
difficulty with movement
gptkbp:treatment physical therapy
supportive care
maintaining independence
occupational therapy
speech therapy
improving quality of life