Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:liver_disease
autoimmune disease |
| gptkbp:affectsOrgan |
liver
|
| gptkbp:alsoKnownAs |
gptkb:primary_biliary_cirrhosis
|
| gptkbp:associatedWith |
anti-mitochondrial antibodies
|
| gptkbp:cause |
cirrhosis
cholestasis |
| gptkbp:characterizedBy |
destruction of intrahepatic bile ducts
|
| gptkbp:commonIn |
gptkb:women
|
| gptkbp:complication |
gptkb:bone
portal hypertension |
| gptkbp:diagnosedBy |
liver biopsy
elevated alkaline phosphatase serum anti-mitochondrial antibody test |
| gptkbp:firstDescribed |
1851
|
| gptkbp:hasNoCure |
true
|
| https://www.w3.org/2000/01/rdf-schema#label |
Primary biliary cholangitis
|
| gptkbp:ICD-10_code |
K74.3
|
| gptkbp:MeSH_ID |
D003937
|
| gptkbp:prevalence |
rare
|
| gptkbp:riskFactor |
family history
other autoimmune diseases |
| gptkbp:symptom |
fatigue
jaundice pruritus |
| gptkbp:treatment |
gptkb:obeticholic_acid
gptkb:ursodeoxycholic_acid liver transplantation |
| gptkbp:typicalOnsetAge |
30-60 years
|
| gptkbp:bfsParent |
gptkb:PBD
|
| gptkbp:bfsLayer |
7
|