Primary Adrenal Insufficiency
GPTKB entity
Statements (48)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
|
| gptkbp:affects |
all ages
adrenal cortex |
| gptkbp:alsoKnownAs |
Addison's disease
|
| gptkbp:associatedWith |
gptkb:autoimmune_polyendocrine_syndromes
|
| gptkbp:canBeFatal |
yes
|
| gptkbp:cause |
tuberculosis
adrenal hemorrhage adrenal metastasis autoimmune destruction of adrenal cortex decreased production of aldosterone decreased production of cortisol |
| gptkbp:complication |
adrenal crisis
|
| gptkbp:diagnosedBy |
gptkb:ACTH_stimulation_test
plasma ACTH measurement serum cortisol measurement |
| gptkbp:firstDescribed |
gptkb:Thomas_Addison
1855 |
| https://www.w3.org/2000/01/rdf-schema#label |
Primary Adrenal Insufficiency
|
| gptkbp:ICD-10_code |
E27.1
|
| gptkbp:labFinding |
gptkb:hypoglycemia
hyponatremia eosinophilia hyperkalemia increased ACTH low cortisol |
| gptkbp:prevalence |
rare
|
| gptkbp:requiresLifelongTreatment |
yes
|
| gptkbp:riskFactor |
metastatic cancer
autoimmune diseases adrenal surgery adrenal hemorrhage tuberculosis infection |
| gptkbp:symptom |
nausea
vomiting abdominal pain fatigue weight loss muscle weakness hypotension hyperpigmentation salt craving |
| gptkbp:treatment |
gptkb:fludrocortisone
hydrocortisone glucocorticoid replacement mineralocorticoid replacement |
| gptkbp:bfsParent |
gptkb:PAE
|
| gptkbp:bfsLayer |
6
|