Pineal Melatonin N-acetyltransferase
GPTKB entity
Statements (22)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:enzyme
|
gptkbp:abbreviation |
AANAT
|
gptkbp:alsoKnownAs |
arylalkylamine N-acetyltransferase
|
gptkbp:associatedWith |
sleep regulation
|
gptkbp:catalyzes |
N-acetylation of serotonin
|
gptkbp:cofactor |
acetyl-CoA
|
gptkbp:discoveredIn |
1960s
|
gptkbp:EC_number |
2.3.1.87
|
gptkbp:expressedIn |
pineal gland
|
gptkbp:foundIn |
vertebrates
|
gptkbp:gene |
AANAT gene
|
gptkbp:highestActivityAt |
night
|
https://www.w3.org/2000/01/rdf-schema#label |
Pineal Melatonin N-acetyltransferase
|
gptkbp:involvedIn |
melatonin biosynthesis
|
gptkbp:mutationAssociatedWith |
sleep disorders
|
gptkbp:product |
gptkb:CoA
gptkb:N-acetylserotonin |
gptkbp:regulates |
light exposure
circadian rhythm |
gptkbp:substrate |
serotonin
|
gptkbp:bfsParent |
gptkb:PMN
|
gptkbp:bfsLayer |
7
|