|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:ATCCode
|
J01CE02
|
|
gptkbp:bioavailability
|
60%
|
|
gptkbp:CASNumber
|
87-08-1
|
|
gptkbp:category
|
narrow-spectrum antibiotic
|
|
gptkbp:chemicalFormula
|
C16H18N2O5S
|
|
gptkbp:color
|
white to off-white powder
|
|
gptkbp:contraindication
|
penicillin allergy
|
|
gptkbp:discoveredBy
|
Hans Margreiter
|
|
gptkbp:eliminationHalfLife
|
30-60 minutes
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Phenoxymethylpenicillin
|
|
gptkbp:IUPACName
|
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
|
|
gptkbp:KEGGID
|
D08320
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:marketedAs
|
1955
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial cell wall synthesis
|
|
gptkbp:meltingPoint
|
178-180°C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
350.39 g/mol
|
|
gptkbp:origin
|
synthetic
|
|
gptkbp:otherName
|
gptkb:Penicillin_V
Penicillin VK
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:proteinBinding
|
80%
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1082
4601
4765
DB00417
|
|
gptkbp:resistantTo
|
beta-lactamase producing bacteria
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
diarrhea
allergic reaction
rash
|
|
gptkbp:solubility
|
slightly soluble in water
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:UNII
|
1W4A77NLL5
|
|
gptkbp:usedFor
|
bacterial infections
streptococcal pharyngitis
rheumatic fever prophylaxis
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
yes
|
|
gptkbp:bfsParent
|
gptkb:J01CE
|
|
gptkbp:bfsLayer
|
7
|