Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
|
| gptkbp:administeredBy |
sodium salt
potassium salt |
| gptkbp:ATCCode |
J01CE01
|
| gptkbp:CASNumber |
61-33-6
|
| gptkbp:category |
natural penicillin
|
| gptkbp:chemicalFormula |
C16H18N2O4S
|
| gptkbp:color |
white to off-white
|
| gptkbp:contraindication |
penicillin allergy
|
| gptkbp:discoveredBy |
gptkb:Alexander_Fleming
|
| gptkbp:excretion |
kidneys
|
| gptkbp:firstIsolatedFrom |
1928
|
| gptkbp:form |
powder
|
| gptkbp:halfLife |
30 minutes
|
| gptkbp:hasInChIKey |
JGS5F2D7IKXTHQ-REOHCLBHSA-N
|
| gptkbp:hasSMILES |
CC1(C)S[C@@H]2[C@H](NC(=O)C3=CC=CC=C3)C(=O)N2[C@H]1C(=O)O
|
| https://www.w3.org/2000/01/rdf-schema#label |
Penicillin G
|
| gptkbp:introduced |
1940s
|
| gptkbp:IUPACName |
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
|
| gptkbp:KEGGID |
D08320
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits bacterial cell wall synthesis
|
| gptkbp:meltingPoint |
163–167 °C
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
334.4 g/mol
|
| gptkbp:notEffectiveAgainst |
penicillinase-producing bacteria
|
| gptkbp:origin |
derived from Penicillium chrysogenum
|
| gptkbp:otherName |
benzylpenicillin
|
| gptkbp:pregnancyCategory |
B (US)
|
| gptkbp:PubChem_CID |
5904
CHEMBL27 5697 DB01053 |
| gptkbp:resistantTo |
inactivated by beta-lactamase
|
| gptkbp:routeOfAdministration |
intramuscular
intravenous |
| gptkbp:sideEffect |
allergic reaction
anaphylaxis rash |
| gptkbp:solubility |
water soluble
|
| gptkbp:spectrum_of_activity |
narrow spectrum
|
| gptkbp:storage |
refrigeration recommended
|
| gptkbp:UNII |
JGS5F2D7IK
|
| gptkbp:usedFor |
gptkb:pneumonia
meningitis syphilis bacterial infections streptococcal infections |
| gptkbp:WHOModelListOfEssentialMedicines |
yes
|
| gptkbp:bfsParent |
gptkb:J01CF
|
| gptkbp:bfsLayer |
7
|