Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
hematologic disorder |
| gptkbp:affects |
white blood cells
neutrophils |
| gptkbp:alsoKnownAs |
gptkb:PHA
Pelger-Huët syndrome |
| gptkbp:characterizedBy |
hyposegmentation of neutrophil nuclei
|
| gptkbp:diagnosedBy |
peripheral blood smear
|
| gptkbp:differentialDiagnosis |
pseudo-Pelger-Huët anomaly
|
| gptkbp:firstDescribed |
1928
G. Huët Karel Pelger |
| https://www.w3.org/2000/01/rdf-schema#label |
Pelger-Huët anomaly
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:morphologicalType |
bilobed neutrophil nuclei
|
| gptkbp:mutationAssociatedWith |
LAMIN B receptor gene
|
| gptkbp:OMIM |
169400
|
| gptkbp:prevalence |
rare
|
| gptkbp:pseudoFormAssociatedWith |
gptkb:acute_myeloid_leukemia
myelodysplastic syndromes |
| gptkbp:significance |
usually benign
|
| gptkbp:bfsParent |
gptkb:Peripheral_Blood_Smear
|
| gptkbp:bfsLayer |
8
|