Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
alkaloid
phosphodiesterase inhibitor vasodilator opioid alkaloid |
| gptkbp:affiliatedWith |
gptkb:isoquinoline_alkaloids
|
| gptkbp:ATCCode |
C04AD03
|
| gptkbp:CASNumber |
58-74-2
|
| gptkbp:chemicalFormula |
C20H21NO4
|
| gptkbp:color |
white
|
| gptkbp:compatibleWith |
cough suppression
analgesia |
| gptkbp:contraindication |
complete atrioventricular block
hypersensitivity to papaverine |
| gptkbp:discoveredBy |
gptkb:Georg_Merck
|
| gptkbp:discoveredIn |
1848
|
| gptkbp:eliminationHalfLife |
1.5–2 hours
|
| gptkbp:excretion |
urine
|
| gptkbp:foundIn |
opium
|
| gptkbp:hasInChIKey |
XQZJHGFQFIBRBM-UHFFFAOYSA-N
|
| gptkbp:hasSMILES |
COC1=CC2=C(C=C1)C=C(C=N2)CC3=CC(=C(C=C3)OC)OC
|
| https://www.w3.org/2000/01/rdf-schema#label |
Papaverine
|
| gptkbp:IUPACName |
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline
|
| gptkbp:KEGGID |
D08367
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:meltingPoint |
147–148 °C
|
| gptkbp:MeSH_ID |
D010213
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
339.39 g/mol
|
| gptkbp:origin |
gptkb:Papaver_somniferum
|
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL1547
4685 DB01113 |
| gptkbp:routeOfAdministration |
oral
intramuscular intravenous |
| gptkbp:sideEffect |
gptkb:arrhythmia
allergic reaction hypotension liver dysfunction |
| gptkbp:solubility |
slightly soluble in water
soluble in ether soluble in alcohol soluble in chloroform |
| gptkbp:UNII |
L5B9O67EHS
|
| gptkbp:usedFor |
treatment of erectile dysfunction
treatment of vasospasm treatment of visceral spasm |
| gptkbp:usedIn |
treatment of cerebral vasospasm
treatment of gastrointestinal spasm treatment of peripheral vascular disease |
| gptkbp:bfsParent |
gptkb:Poppy
|
| gptkbp:bfsLayer |
5
|