|
gptkbp:instanceOf
|
gptkb:vasodilator
gptkb:phosphodiesterase_inhibitor
gptkb:opioid_alkaloid
gptkb:alkaloid
|
|
gptkbp:affiliatedWith
|
gptkb:isoquinoline_alkaloids
|
|
gptkbp:ATCCode
|
C04AD03
|
|
gptkbp:CASNumber
|
58-74-2
|
|
gptkbp:chemicalFormula
|
C20H21NO4
|
|
gptkbp:color
|
white
|
|
gptkbp:compatibleWith
|
cough suppression
analgesia
|
|
gptkbp:contraindication
|
complete atrioventricular block
hypersensitivity to papaverine
|
|
gptkbp:discoveredBy
|
gptkb:Georg_Merck
|
|
gptkbp:discoveredIn
|
1848
|
|
gptkbp:eliminationHalfLife
|
1.5–2 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:foundIn
|
opium
|
|
gptkbp:hasInChIKey
|
XQZJHGFQFIBRBM-UHFFFAOYSA-N
|
|
gptkbp:hasSMILES
|
COC1=CC2=C(C=C1)C=C(C=N2)CC3=CC(=C(C=C3)OC)OC
|
|
gptkbp:IUPACName
|
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline
|
|
gptkbp:KEGGID
|
D08367
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:meltingPoint
|
147–148 °C
|
|
gptkbp:MeSH_ID
|
D010213
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
339.39 g/mol
|
|
gptkbp:origin
|
gptkb:Papaver_somniferum
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1547
4685
DB01113
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
gptkb:arrhythmia
allergic reaction
hypotension
liver dysfunction
|
|
gptkbp:solubility
|
slightly soluble in water
soluble in ether
soluble in alcohol
soluble in chloroform
|
|
gptkbp:UNII
|
L5B9O67EHS
|
|
gptkbp:usedFor
|
treatment of erectile dysfunction
treatment of vasospasm
treatment of visceral spasm
|
|
gptkbp:usedIn
|
treatment of cerebral vasospasm
treatment of gastrointestinal spasm
treatment of peripheral vascular disease
|
|
gptkbp:bfsParent
|
gptkb:Poppy
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Papaverine
|