Paget's disease of the nipple

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:disease gptkb:skin breast disease
gptkbp:affects	gptkb:nipple areola
gptkbp:associatedWith	underlying breast cancer
gptkbp:commonIn	gptkb:women
gptkbp:diagnosedBy	clinical examination biopsy mammography
gptkbp:differentialDiagnosis	gptkb:eczema gptkb:contact_dermatitis psoriasis inflammatory breast cancer
gptkbp:eponymOf	gptkb:James_Paget
gptkbp:firstDescribed	gptkb:Sir_James_Paget 1874
gptkbp:hasType	gptkb:Paget_cells
https://www.w3.org/2000/01/rdf-schema#label	Paget's disease of the nipple
gptkbp:ICD-10_code	C50.0
gptkbp:incidence	1-4% of all breast cancers
gptkbp:MeSH_ID	gptkb:D010141
gptkbp:occurredIn	gptkb:ductal_carcinoma_in_situ men invasive breast carcinoma
gptkbp:OMIM	603690
gptkbp:Paget_cells_are	large cells with clear cytoplasm
gptkbp:Paget_cells_are_found_in	epidermis of the nipple
gptkbp:prevalence	rare
gptkbp:prognosis	depends on underlying cancer
gptkbp:riskFactor	family history of breast cancer female gender age over 50 personal history of breast cancer
gptkbp:symptom	bleeding itching redness ulceration eczema-like changes of the nipple flaking skin nipple discharge
gptkbp:synonym	gptkb:mammary_Paget's_disease
gptkbp:treatment	surgery radiation therapy chemotherapy hormonal therapy mastectomy
gptkbp:bfsParent	gptkb:nipple
gptkbp:bfsLayer	6