Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:abbreviation |
gptkb:praziquantel
|
| gptkbp:ATCCode |
P02BA01
|
| gptkbp:bioavailability |
~80%
|
| gptkbp:CASNumber |
55268-74-1
|
| gptkbp:chemicalFormula |
C19H24N2O2
|
| gptkbp:developedBy |
gptkb:Merck_KGaA
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:eliminationHalfLife |
0.8–1.5 hours
|
| https://www.w3.org/2000/01/rdf-schema#label |
PZQ
|
| gptkbp:includedIn |
gptkb:World_Health_Organization's_List_of_Essential_Medicines
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
increases permeability of cell membranes to calcium ions in parasites
|
| gptkbp:metabolism |
liver
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
nausea
abdominal pain headache |
| gptkbp:usedFor |
treatment of liver fluke infections
treatment of schistosomiasis treatment of tapeworm infections |
| gptkbp:bfsParent |
gptkb:Praziquantel
gptkb:praziquantel |
| gptkbp:bfsLayer |
7
|