Statements (60)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
phosphoinositide metabolism
|
| gptkbp:function |
phosphatidylinositol phosphate kinase activity
|
| gptkbp:fuselage_material |
phosphatidylinositol
|
| gptkbp:genetic_studies |
associated with diseases
|
| gptkbp:has_function |
phosphorylation of inositol lipids
|
| gptkbp:has_role |
regulating cellular processes
|
| gptkbp:has_website |
PH domain
kinase domain |
| https://www.w3.org/2000/01/rdf-schema#label |
PIP5 K2 A
|
| gptkbp:initiated_by |
small molecule inhibitors
|
| gptkbp:interacts_with |
gptkb:PIP5_K1_A
|
| gptkbp:involved_in |
apoptosis
cell proliferation cell signaling |
| gptkbp:is_expressed_in |
gptkb:sports_car
gptkb:Brain gptkb:Heart kidney liver various tissues |
| gptkbp:is_involved_in |
gptkb:diabetes
DNA repair cell cycle regulation cell differentiation cellular homeostasis cytoskeletal organization immune response neurotransmitter release signal transduction chronic diseases inflammation metabolic syndrome obesity stress response cardiovascular diseases tumorigenesis cellular aging membrane dynamics endocytosis vesicle trafficking angiogenesis cell adhesion cell migration metastasis neurodegeneration exocytosis metabolic regulation hormonal signaling apoptotic signaling |
| gptkbp:is_part_of |
lipid signaling
|
| gptkbp:is_regulated_by |
growth factors
hormones |
| gptkbp:located_in |
gptkb:Atom
|
| gptkbp:orthologs |
gptkb:PIP5_K2_B
|
| gptkbp:pathway |
PI3 K-Akt signaling pathway
|
| gptkbp:promoter |
PIP5 K2 A gene
|
| gptkbp:regulates |
phosphatidylinositol 4,5-bisphosphate levels
|
| gptkbp:bfsParent |
gptkb:PIK3_CA
|
| gptkbp:bfsLayer |
6
|