Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gene therapy
|
| gptkbp:amendedBy |
CD52 knockout
TCR knockout |
| gptkbp:antigen |
gptkb:CD19
|
| gptkbp:clinicalTrialPhase |
Phase 1/2a
|
| gptkbp:developedBy |
Precision BioSciences
|
| gptkbp:geneEditingTechnology |
ARCUS
|
| https://www.w3.org/2000/01/rdf-schema#label |
PBCAR19B
|
| gptkbp:indication |
B-cell malignancies
Acute lymphoblastic leukemia Non-Hodgkin lymphoma |
| gptkbp:mechanismOfAction |
CD19-directed cytolysis
|
| gptkbp:routeOfAdministration |
Intravenous
|
| gptkbp:source |
Allogeneic
|
| gptkbp:status |
Investigational
|
| gptkbp:treatment |
Allogeneic CAR-T
|
| gptkbp:bfsParent |
gptkb:Precision_Biosciences
|
| gptkbp:bfsLayer |
7
|