Orotidine-5'-phosphate decarboxylase
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
ODCase
OMP decarboxylase |
| gptkbp:biologicalProcess |
lyase activity
|
| gptkbp:catalyzes |
decarboxylation of orotidine 5'-monophosphate to uridine 5'-monophosphate
|
| gptkbp:compatibleWith |
cofactors
|
| gptkbp:EC_number |
4.1.1.23
|
| gptkbp:foundIn |
all domains of life
|
| gptkbp:gene |
UMPS (in humans)
URA3 (in yeast) |
| https://www.w3.org/2000/01/rdf-schema#label |
Orotidine-5'-phosphate decarboxylase
|
| gptkbp:inhibitedBy |
6-azauridine monophosphate
|
| gptkbp:involves |
pyrimidine biosynthesis
|
| gptkbp:part_of |
UMP synthase (in humans)
|
| gptkbp:PDB |
1DQX
|
| gptkbp:product |
uridine 5'-monophosphate
|
| gptkbp:remarkable_for |
one of the highest known rate enhancements for an enzyme
|
| gptkbp:substrate |
orotidine 5'-monophosphate
|
| gptkbp:systematicName |
orotidine-5'-phosphate carboxy-lyase
|
| gptkbp:type |
OMP → UMP + CO2
|
| gptkbp:UniProtID |
P11172 (human)
|
| gptkbp:bfsParent |
gptkb:URA3
|
| gptkbp:bfsLayer |
7
|