Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
neuropathological condition
|
| gptkbp:affectedBrainRegion |
gptkb:posterior_cingulate_cortex
retrosplenial cortex |
| gptkbp:alsoKnownAs |
NMDA antagonist neurotoxicity
|
| gptkbp:associatedWith |
excitotoxicity
|
| gptkbp:characterizedBy |
vacuolization of neurons
|
| gptkbp:compatibleWith |
primates (including humans)
|
| gptkbp:designer |
yes
|
| gptkbp:discoveredBy |
gptkb:John_W._Olney
|
| gptkbp:firstDescribed |
1989
|
| https://www.w3.org/2000/01/rdf-schema#label |
Olney's lesions
|
| gptkbp:inducedBy |
gptkb:ketamine
dissociative anesthetics phencyclidine (PCP) NMDA receptor antagonists dizocilpine (MK-801) |
| gptkbp:observedBy |
rodents
|
| gptkbp:relevanceToHumans |
unknown
|
| gptkbp:studiedIn |
neurotoxicity research
|
| gptkbp:bfsParent |
gptkb:John_Olney
|
| gptkbp:bfsLayer |
6
|