Ofev

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:activeIngredient gptkb:nintedanib
gptkbp:approvalYear 2014
gptkbp:ATCCode L01XE31
gptkbp:CASNumber 656247-17-5
gptkbp:chemicalFormula C31H33N5O4
gptkbp:drugClass antifibrotic agent
https://www.w3.org/2000/01/rdf-schema#label Ofev
gptkbp:legalStatus prescription only
gptkbp:manufacturer gptkb:Boehringer_Ingelheim
gptkbp:mechanismOfAction gptkb:receptor_tyrosine_kinase
gptkbp:pregnancyCategory D (US)
gptkbp:routeOfAdministration oral
gptkbp:sideEffect nausea
vomiting
diarrhea
liver enzyme elevation
gptkbp:tradeNameOf gptkb:nintedanib
gptkbp:usedFor idiopathic pulmonary fibrosis
systemic sclerosis-associated interstitial lung disease
chronic fibrosing interstitial lung diseases with a progressive phenotype
gptkbp:bfsParent gptkb:Boehringer_Ingelheim
gptkbp:bfsLayer 6