Statements (22)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:associatedWith |
gptkb:COVID-19
|
gptkbp:discoveredIn |
2019
|
gptkbp:downregulatedIn |
MHC-I expression
|
gptkbp:encodedBy |
gptkb:COVID-19
|
gptkbp:function |
immune evasion
|
gptkbp:gene |
ORF8
|
https://www.w3.org/2000/01/rdf-schema#label |
ORF8 protein
|
gptkbp:interactsWith |
MHC-I molecules
|
gptkbp:involves |
modulation of host immune response
|
gptkbp:length |
121 amino acids
|
gptkbp:location |
gptkb:SARS-CoV-2_genome
|
gptkbp:mutationAssociatedWith |
L84S
Q27stop frequent deletions |
gptkbp:orthologIn |
SARS-CoV ORF8a
SARS-CoV ORF8b |
gptkbp:presentIn |
gptkb:Betacoronavirus
|
gptkbp:secretes |
yes
|
gptkbp:structure |
immunoglobulin-like fold
|
gptkbp:bfsParent |
gptkb:SARS-CoV-2_virion
|
gptkbp:bfsLayer |
7
|