Noradrenaline

GPTKB entity

Statements (36)
Predicate Object
gptkbp:instanceOf hormone
neurotransmitter
gptkbp:actsOn adrenergic receptors
gptkbp:ATCCode C01CA03
gptkbp:biosynthesized_from gptkb:dopamine_beta-hydroxylase
gptkbp:CASNumber 51-41-2
gptkbp:chemicalFormula C8H11NO3
gptkbp:color white to off-white (as solid)
gptkbp:degradedBy gptkb:monoamine_oxidase
catechol-O-methyltransferase
gptkbp:discoveredBy gptkb:Ulf_von_Euler
gptkbp:discoveredIn 1946
gptkbp:drugIndication cardiac arrest
hypotension
gptkbp:foundIn gptkb:locus_coeruleus
gptkb:adrenal_medulla
gptkbp:function increases blood pressure
increases heart rate
modulates arousal
modulates attention
modulates stress response
triggers fight-or-flight response
https://www.w3.org/2000/01/rdf-schema#label Noradrenaline
gptkbp:IUPACName 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol
gptkbp:meltingPoint 248 °C
gptkbp:MeSH_ID D009638
gptkbp:otherName norepinephrine
gptkbp:predecessor dopamine
gptkbp:PubChem_CID 439260
CHEBI:33569
CHEMBL414
gptkbp:solubility water soluble
gptkbp:UNII X4W7ZR7023
gptkbp:usedAsDrug yes
gptkbp:bfsParent gptkb:Adrenal_Gland
gptkbp:bfsLayer 6