|
gptkbp:instanceOf
|
substance abuse
alkaloid
stimulant
|
|
gptkbp:actsOn
|
nicotinic acetylcholine receptors
|
|
gptkbp:addiction
|
true
|
|
gptkbp:affects
|
central nervous system
cardiovascular system
|
|
gptkbp:aroma
|
tobacco-like
|
|
gptkbp:boilingPoint
|
247 °C
|
|
gptkbp:CASNumber
|
54-11-5
|
|
gptkbp:cause
|
increased heart rate
increased blood pressure
dopamine release
|
|
gptkbp:chemicalFormula
|
gptkb:C10H14N2
|
|
gptkbp:color
|
colorless to yellowish oily liquid
|
|
gptkbp:density
|
1.01 g/cm³
|
|
gptkbp:discoveredBy
|
gptkb:Karl_Ludwig_Reimann
gptkb:Wilhelm_Heinrich_Posselt
|
|
gptkbp:discoveredIn
|
1828
|
|
gptkbp:firstIsolatedFrom
|
gptkb:tobacco_plant
|
|
gptkbp:foundIn
|
gptkb:tobacco
nightshade family plants
|
|
gptkbp:halfLife
|
1–2 hours
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Nicotine
|
|
gptkbp:IUPACName
|
gptkb:3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
|
|
gptkbp:LD50
|
50 mg/kg
|
|
gptkbp:legalStatus
|
regulated
|
|
gptkbp:main_component_of
|
snuff
e-cigarettes
cigarettes
chewing tobacco
|
|
gptkbp:meltingPoint
|
-79 °C
|
|
gptkbp:metabolism
|
gptkb:cotinine
liver
|
|
gptkbp:molecularWeight
|
162.23 g/mol
|
|
gptkbp:namedAfter
|
gptkb:Jean_Nicot
|
|
gptkbp:producedBy
|
gptkb:Nicotiana_rustica
gptkb:Nicotiana_tabacum
|
|
gptkbp:routeOfAdministration
|
oral
inhalation
transdermal
intranasal
sublingual
|
|
gptkbp:solubility
|
soluble in water
soluble in ether
soluble in alcohol
|
|
gptkbp:toxicity
|
toxic in high doses
|
|
gptkbp:usedFor
|
gptkb:entomologist
stimulant
|
|
gptkbp:bfsParent
|
gptkb:tobacco
|
|
gptkbp:bfsLayer
|
5
|