Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetically modified organism
laboratory mouse model |
| gptkbp:createdBy |
gene targeting
|
| gptkbp:geneticBackground |
gptkb:Mus_musculus
|
| gptkbp:hasGeneKnockout |
Nf1
|
| gptkbp:hasModel |
malignant peripheral nerve sheath tumors
optic glioma human neurofibromatosis type 1 |
| gptkbp:hasPhenotype |
reduced lifespan
learning deficits abnormal neural development increased tumor formation |
| https://www.w3.org/2000/01/rdf-schema#label |
Nf1 knockout mouse
|
| gptkbp:relatedTo |
gptkb:NF1_gene
gptkb:Ras_signaling_pathway |
| gptkbp:usedFor |
cancer research
neuroscience research neurofibromatosis type 1 research |
| gptkbp:usedIn |
preclinical drug testing
|
| gptkbp:bfsParent |
gptkb:NF1_gene
|
| gptkbp:bfsLayer |
7
|