|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CADASIL_protein
gptkb:Notch_homolog_3
hN3
|
|
gptkbp:associatedWith
|
gptkb:CADASIL
stroke
vascular dementia
|
|
gptkbp:biologicalProcess
|
cell differentiation
signal transduction
neurogenesis
receptor activity
|
|
gptkbp:discoveredBy
|
Notch gene family researchers
|
|
gptkbp:encodes
|
gptkb:Neurogenic_locus_notch_homolog_protein_3
|
|
gptkbp:Entrez_Gene_ID
|
4854
ENSG00000074181
|
|
gptkbp:expressedIn
|
vascular smooth muscle cells
|
|
gptkbp:function
|
cell fate determination
arterial smooth muscle cell function
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
GO:0005886
GO:0005515
GO:0003674
GO:0004888
GO:0005575
GO:0005887
GO:0005888
GO:0005889
GO:0005890
GO:0005891
GO:0007154
GO:0007219
GO:0007399
GO:0009987
GO:0048666
|
|
gptkbp:hasGeneCardsID
|
gptkb:NOTCH3
|
|
gptkbp:hasMIMNumber
|
600276
|
|
gptkbp:hasRefSeqID
|
NM_000435
|
|
gptkbp:HGNC_ID
|
7882
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NOTCH3
|
|
gptkbp:KEGGID
|
hsa:4854
|
|
gptkbp:length
|
2321 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19
19p13.12
|
|
gptkbp:mutationAssociatedWith
|
gptkb:CADASIL
|
|
gptkbp:OMIM
|
600276
|
|
gptkbp:orthologInMouse
|
gptkb:Notch3
|
|
gptkbp:PDB
|
4ZLP
|
|
gptkbp:proteinFamily
|
gptkb:Notch_receptor_family
|
|
gptkbp:Reactome
|
R-HSA-1980143
|
|
gptkbp:UniProtID
|
Q9UM47
|
|
gptkbp:bfsParent
|
gptkb:19p13.3
gptkb:chromosome_19
|
|
gptkbp:bfsLayer
|
6
|