Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
toxic metabolite |
| gptkbp:accumulates_when |
glutathione is depleted
|
| gptkbp:cause |
liver damage
|
| gptkbp:chemicalFormula |
C8H7NO2
|
| gptkbp:contains_functional_group |
quinone imine
|
| gptkbp:detoxified_by |
glutathione
|
| gptkbp:discoveredBy |
1970s
|
| https://www.w3.org/2000/01/rdf-schema#label |
NAPQI
|
| gptkbp:IUPACName |
N-acetyl-p-benzoquinone imine
|
| gptkbp:molecularWeight |
149.15 g/mol
|
| gptkbp:otherName |
N-acetyl-p-benzoquinone imine
paracetamol metabolite |
| gptkbp:producedBy |
gptkb:cytochrome_P450_enzymes
|
| gptkbp:produces |
gptkb:paracetamol
acetaminophen |
| gptkbp:PubChem_CID |
1983
CHEBI:132968 |
| gptkbp:role_in_medicine |
responsible for acetaminophen overdose toxicity
|
| gptkbp:toxicity |
hepatotoxic
|
| gptkbp:UNII |
8Y7T2UQY6X
|
| gptkbp:bfsParent |
gptkb:paracetamol
|
| gptkbp:bfsLayer |
6
|