NAD-dependent histone deacetylase
GPTKB entity
Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
sirtuin
SIRT |
| gptkbp:catalyzes |
deacetylation of histones
|
| gptkbp:cofactor |
NAD+
|
| gptkbp:EC_number |
3.5.1.98
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:hasRole |
aging
DNA repair metabolism |
| https://www.w3.org/2000/01/rdf-schema#label |
NAD-dependent histone deacetylase
|
| gptkbp:inhibitedBy |
nicotinamide
|
| gptkbp:involves |
chromatin remodeling
|
| gptkbp:member |
sirtuin family
|
| gptkbp:produces |
nicotinamide
O-acetyl-ADP-ribose deacetylated histone |
| gptkbp:regulates |
gene expression
|
| gptkbp:bfsParent |
gptkb:SIR-2
|
| gptkbp:bfsLayer |
7
|