|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:antibiotic
|
|
gptkbp:approvedBy
|
1985
|
|
gptkbp:ATCCode
|
D06AX09
|
|
gptkbp:brand
|
Bactroban
Centany
|
|
gptkbp:CASNumber
|
12650-69-0
|
|
gptkbp:chemicalClass
|
pseudomonic acid
|
|
gptkbp:concerns
|
increasing mupirocin resistance in MRSA
|
|
gptkbp:contraindication
|
hypersensitivity to mupirocin
|
|
gptkbp:discoveredBy
|
gptkb:Beecham_Group
|
|
gptkbp:eliminationHalfLife
|
20-40 minutes
|
|
gptkbp:form
|
gptkb:butter
gptkb:hospital
|
|
gptkbp:hasMolecularFormula
|
C26H44O9
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Mupirocin
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial isoleucyl-tRNA synthetase
|
|
gptkbp:metabolism
|
rapidly metabolized to monic acid
|
|
gptkbp:origin
|
produced by Pseudomonas fluorescens
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:routeOfAdministration
|
topical
|
|
gptkbp:sideEffect
|
itching
skin irritation
burning sensation
|
|
gptkbp:usedFor
|
treatment of MRSA colonization
treatment of impetigo
treatment of skin infections
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
yes
|
|
gptkbp:bfsParent
|
gptkb:Streptomyces_species
|
|
gptkbp:bfsLayer
|
6
|