Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:virus
|
| gptkbp:affects |
mice
|
| gptkbp:belongs_to |
Retroviridae family
|
| gptkbp:can_detect |
PCR methods
|
| gptkbp:cause |
mammary tumors in mice
|
| gptkbp:communication_system |
breast milk
|
| gptkbp:discovered_by |
1970s
|
| gptkbp:has_genome |
RNA genome
|
| gptkbp:has_impact_on |
immune response in mice
|
| https://www.w3.org/2000/01/rdf-schema#label |
Mouse mammary tumor virus
|
| gptkbp:initiated_by |
heat treatment
antiviral drugs |
| gptkbp:investigates |
biomarker discovery
therapeutic interventions |
| gptkbp:is_a |
oncogenic virus
|
| gptkbp:is_analyzed_in |
gene therapy approaches
|
| gptkbp:is_associated_with |
cell cycle dysregulation
oncogenic potential chronic infection in mice immunosuppression in mice metastatic behavior in tumors viral replication in host cells |
| gptkbp:is_characterized_by |
high mutation rate
envelope proteins specific receptor usage viral envelope glycoproteins viral integration into host genome |
| gptkbp:is_considered_as |
a model for human breast cancer research
|
| gptkbp:is_known_for |
inducing mammary gland hyperplasia
|
| gptkbp:is_linked_to |
cell signaling pathways
immune evasion strategies epigenetic changes in host cells genetic susceptibility in mice hormonal influences in tumor development tumor suppressor gene alterations |
| gptkbp:is_part_of |
viral evolution studies
viral pathogenesis studies cancer biology research mouse model studies |
| gptkbp:is_recognized_by |
serological tests
|
| gptkbp:is_related_to |
human immunodeficiency virus
|
| gptkbp:is_studied_for |
vaccine development
tumor microenvironment interactions viral oncogenesis host-virus interactions molecular mechanisms of oncogenesis tumorigenesis mechanisms |
| gptkbp:is_studied_in |
laboratory settings
|
| gptkbp:is_used_in |
cancer research
preclinical trials |
| gptkbp:participated_in |
malignant tumors
|
| gptkbp:transmission |
horizontal transmission
|
| gptkbp:bfsParent |
gptkb:Retroviridae
|
| gptkbp:bfsLayer |
5
|