Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:application |
pharmaceutical synthesis
synthesis of natural products |
| gptkbp:byproduct |
gptkb:triphenylphosphine_oxide
hydrazine derivative |
| gptkbp:category |
organic chemistry
named reaction |
| gptkbp:discoveredIn |
1967
|
| gptkbp:has_stereochemistry |
inversion of configuration
|
| https://www.w3.org/2000/01/rdf-schema#label |
Mitsunobu reaction
|
| gptkbp:limitation |
requires acidic pronucleophile
sensitive to steric hindrance |
| gptkbp:mechanismOfAction |
nucleophilic substitution
|
| gptkbp:namedAfter |
gptkb:Oyo_Mitsunobu
|
| gptkbp:reactant |
gptkb:triphenylphosphine
gptkb:beer acidic pronucleophile diethyl azodicarboxylate |
| gptkbp:solvent |
gptkb:tetrahydrofuran
dichloromethane |
| gptkbp:usedFor |
conversion of alcohols into esters
conversion of alcohols into various functional groups |
| gptkbp:bfsParent |
gptkb:triphenylphosphine
gptkb:Roush–Mitsunobu_reaction |
| gptkbp:bfsLayer |
7
|