Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:Corticosteroid
|
| gptkbp:approvedBy |
1955
|
| gptkbp:ATCCode |
H02AB04
|
| gptkbp:brand |
Depo-Medrol
Medrol Solu-Medrol |
| gptkbp:CASNumber |
83-43-2
|
| gptkbp:contraindication |
systemic fungal infections
hypersensitivity to methylprednisolone |
| gptkbp:discoveredBy |
gptkb:Pfizer
|
| gptkbp:drugClass |
gptkb:Corticosteroid
|
| gptkbp:eliminationHalfLife |
2.4 to 3.5 hours
|
| gptkbp:excretion |
urine
|
| gptkbp:hasMolecularFormula |
C22H30O5
|
| https://www.w3.org/2000/01/rdf-schema#label |
Methylprednisolone
|
| gptkbp:KEGGID |
D00436
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
glucocorticoid receptor agonist
|
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
C
|
| gptkbp:PubChem_CID |
6741
CHEMBL1200698 DB00959 |
| gptkbp:routeOfAdministration |
oral
intramuscular intravenous |
| gptkbp:sideEffect |
gptkb:bone
immunosuppression hypertension mood changes weight gain insomnia hyperglycemia gastric irritation |
| gptkbp:synonym |
Depo-Medrol
Medrol Solu-Medrol 6α-methylprednisolone |
| gptkbp:UNII |
J8A7G3Y4QJ
|
| gptkbp:usedFor |
autoimmune diseases
lupus rheumatoid arthritis allergic reactions organ transplant rejection asthma exacerbations inflammatory conditions dermatologic diseases multiple sclerosis relapses |
| gptkbp:bfsParent |
gptkb:Zentiva
|
| gptkbp:bfsLayer |
7
|