Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
opioid
|
| gptkbp:alsoKnownAs |
gptkb:Demerol
pethidine |
| gptkbp:ATCCode |
N02AB02
|
| gptkbp:CASNumber |
57-42-1
|
| gptkbp:chemicalClass |
gptkb:4-phenylpiperidine
|
| gptkbp:contraindication |
MAOI use
hypersensitivity severe respiratory depression |
| gptkbp:developedBy |
gptkb:IG_Farben
|
| gptkbp:discoveredBy |
gptkb:Otto_Eisleb
|
| gptkbp:discoveredIn |
1939
|
| gptkbp:eliminationHalfLife |
2.5-4 hours
|
| gptkbp:excretion |
urine
|
| gptkbp:firstSynthesized |
1939
|
| gptkbp:hasMolecularFormula |
C15H21NO2
|
| https://www.w3.org/2000/01/rdf-schema#label |
Meperidine
|
| gptkbp:KEGGID |
D08109
|
| gptkbp:legalStatus |
gptkb:Schedule_II_(US)
Prescription only (various countries) |
| gptkbp:mechanismOfAction |
mu-opioid receptor agonist
|
| gptkbp:meltingPoint |
186-189°C (hydrochloride salt)
|
| gptkbp:metabolism |
liver
normeperidine |
| gptkbp:notRecommendedFor |
elderly patients
chronic pain |
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:PubChem_CID |
4058
CHEMBL1531 DB00454 |
| gptkbp:riskFactor |
addiction
abuse overdose seizures (with high doses or renal impairment) serotonin syndrome (with serotonergic drugs) |
| gptkbp:routeOfAdministration |
oral
intramuscular subcutaneous intravenous |
| gptkbp:sideEffect |
nausea
vomiting constipation dizziness drowsiness respiratory depression |
| gptkbp:solubility |
soluble in water (hydrochloride salt)
|
| gptkbp:UNII |
UY443GRB0G
|
| gptkbp:usedFor |
pain management
|
| gptkbp:usedIn |
preoperative sedation
obstetric analgesia |
| gptkbp:bfsParent |
gptkb:Schedule_II
|
| gptkbp:bfsLayer |
6
|