Medroxyprogesterone acetate

URI: https://gptkb.org/entity/Medroxyprogesterone_acetate
GPTKB entity
Statements (49)
Predicate Object
gptkbp:instanceOf synthetic progestin
hormonal medication
gptkbp:approvedBy gptkb:United_States
gptkbp:ATCCode gptkb:G03AC06
gptkbp:brand gptkb:Depo-Provera
gptkb:Depo-SubQ_Provera_104
Provera
gptkbp:CASNumber gptkb:71-58-9
gptkbp:chemicalClass pregnane steroid
gptkbp:contraindication pregnancy
liver dysfunction
active thrombophlebitis
gptkbp:discoveredBy gptkb:Upjohn
gptkbp:eliminationHalfLife 6-7 days (IM)
gptkbp:hasMolecularFormula C24H34O4
https://www.w3.org/2000/01/rdf-schema#label Medroxyprogesterone acetate
gptkbp:introducedIn 1958
gptkbp:IUPACName (6α)-17-acetoxy-6-methylpregn-4-ene-3,20-dione
gptkbp:KEGGID gptkb:D00429
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction progestogenic activity
gptkbp:meltingPoint 205-210°C
gptkbp:metabolism liver
gptkbp:pregnancyCategory gptkb:X_(US)
gptkb:D_(Australia)
gptkbp:PubChem_CID gptkb:DB00603
6624
CHEMBL1200698
gptkbp:relatedTo gptkb:progesterone
medroxyprogesterone
gptkbp:routeOfAdministration oral
intramuscular injection
subcutaneous injection
gptkbp:sideEffect headache
mood changes
weight gain
decreased bone density
menstrual irregularities
gptkbp:solubility practically insoluble in water
gptkbp:UNII 8C5M2CQZ6R
gptkbp:usedFor contraception
hormone replacement therapy
treatment of certain cancers
treatment of endometriosis
treatment of abnormal uterine bleeding
treatment of amenorrhea
gptkbp:WHOModelListOfEssentialMedicines true
gptkbp:bfsParent gptkb:Viatris
gptkbp:bfsLayer 8