Mebendazole

GPTKB entity

Statements (59)
Predicate Object
gptkbp:instance_of gptkb:mythological_figure
gptkbp:bfsLayer 5
gptkbp:bfsParent gptkb:Ciba-Geigy
gptkbp:activities inhibits microtubule synthesis
gptkbp:appointed_by oral tablet
gptkbp:approves gptkb:1971
gptkb:FDA
gptkbp:brand Vermox
gptkbp:clinical_trial Phase IV
elderly patients
pediatric patients
adult patients
immunocompromised patients
gptkbp:color gptkb:white
gptkbp:contraindication pregnancy
lactation
gptkbp:developed_by gptkb:Johnson_&_Johnson
gptkbp:dissolved poorly soluble in water
gptkbp:dosage_form gptkb:tablet
suspension
100 mg twice daily
500 mg single dose for some infections
gptkbp:excretion urine
gptkbp:flavor gptkb:beer
https://www.w3.org/2000/01/rdf-schema#label Mebendazole
gptkbp:ingredients C16 H19 N3 O3
gptkbp:interacts_with gptkb:phenytoin
gptkb:phenobarbital
gptkb:warfarin
gptkbp:invention generic available since 1982
patented until 1981
gptkbp:is_atype_of P02 C A01
gptkbp:is_available_in tablets
suspension
gptkbp:is_available_on generic drug
gptkbp:is_used_for treating parasitic worm infections
gptkbp:level 5.5
gptkbp:lifespan 2.5 to 5 hours
gptkbp:manager oral
gptkbp:metabolism liver
gptkbp:research_areas pharmacology
tropical medicine
parasitology
gptkbp:safety_features Category C
gptkbp:side_effect dizziness
headache
nausea
abdominal pain
allergic reactions
diarrhea
liver toxicity
skin rash
gptkbp:storage room temperature
gptkbp:treatment ascariasis
strongyloidiasis
enterobiasis
hookworm infection
whipworm infection
gptkbp:type_of 31431-39-7