MRTX1719

GPTKB entity

Statements (20)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkbp:CASNumber 2419600-41-1
gptkbp:clinicalTrialPhase Phase 1/2
gptkbp:developedBy gptkb:Mirati_Therapeutics
gptkbp:hasApplication gptkb:cancer
gptkbp:hasInChIKey QJQZQJQJQJQJQJ-QJQJQJQJSA-N
gptkbp:hasMolecularFormula C17H18ClN5O
gptkbp:hasSMILES CC(C)N1C=NC2=C1C(=O)N(C(=N2)C)C3=CC=C(C=C3)Cl
gptkbp:heldBy PRMT5 inhibitor
https://www.w3.org/2000/01/rdf-schema#label MRTX1719
gptkbp:indication solid tumors
gptkbp:IUPACName (3S,6S)-6-(4-chlorophenyl)-3-methyl-1-(1-methylethyl)-3,6-dihydro-2H-pyrazolo[3,4-d]pyrimidin-4(5H)-one
gptkbp:mechanismOfAction inhibits PRMT5-MTA complex
gptkbp:PubChem_CID 114442324
155349727
gptkbp:routeOfAdministration oral
gptkbp:status investigational drug
gptkbp:target PRMT5
gptkbp:bfsParent gptkb:Mirati_Therapeutics
gptkbp:bfsLayer 7