MPL (monophosphoryl lipid A)
GPTKB entity
Statements (19)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
adjuvant
lipid A derivative |
| gptkbp:activatedBy |
gptkb:Toll-like_receptor_4
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:CASNumber |
720704-12-1
|
| gptkbp:component |
AS01 adjuvant system
AS04 adjuvant system |
| gptkbp:derivedFrom |
lipopolysaccharide
|
| gptkbp:discoveredBy |
Ribi ImmunoChem Research
|
| gptkbp:hasMolecularFormula |
C82H162N2O19P
|
| https://www.w3.org/2000/01/rdf-schema#label |
MPL (monophosphoryl lipid A)
|
| gptkbp:promotion |
immune response
|
| gptkbp:reduces |
endotoxicity
|
| gptkbp:synonym |
3-O-desacyl-4'-monophosphoryl lipid A
|
| gptkbp:usedIn |
gptkb:Shingrix_vaccine
vaccines Cervarix vaccine |
| gptkbp:bfsParent |
gptkb:AS01B_adjuvant
|
| gptkbp:bfsLayer |
8
|