Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
endocrine neoplasia syndrome |
| gptkbp:alsoKnownAs |
gptkb:Multiple_Endocrine_Neoplasia_type_2
|
| gptkbp:characterizedBy |
gptkb:pheochromocytoma
gptkb:medullary_thyroid_carcinoma parathyroid adenoma |
| gptkbp:diagnosedBy |
genetic testing
|
| gptkbp:firstDescribed |
gptkb:John_Sipple
|
| https://www.w3.org/2000/01/rdf-schema#label |
MEN2 syndrome
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:managedBy |
endocrinologist
|
| gptkbp:mutationAssociatedWith |
gptkb:RET_gene
|
| gptkbp:OMIM |
171400
|
| gptkbp:onset |
childhood or early adulthood
|
| gptkbp:prevalence |
rare
|
| gptkbp:riskFactor |
increased risk of thyroid cancer
|
| gptkbp:subspecies |
gptkb:MEN2A
gptkb:MEN2B gptkb:FMTC |
| gptkbp:treatment |
prophylactic thyroidectomy
surgical removal of pheochromocytoma |
| gptkbp:bfsParent |
gptkb:Medullary_thyroid_carcinoma
gptkb:pheochromocytoma |
| gptkbp:bfsLayer |
7
|