MAGE family

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:compatibleWith normal somatic tissues
gptkbp:containsGene MAGEA1
MAGEA10
MAGEA2
MAGEA3
MAGEA4
MAGEA6
MAGEB1
MAGEB2
MAGEB3
MAGEC1
MAGEC2
gptkbp:discoveredIn melanoma
gptkbp:expressedIn gptkb:testis
various tumors
gptkbp:foundIn humans
mammals
gptkbp:fullName Melanoma Antigen Gene family
gptkbp:function gptkb:tumor_antigen
immune response modulation
gptkbp:geneFamilyType multigene family
gptkbp:HGNC_ID 6805
https://www.w3.org/2000/01/rdf-schema#label MAGE family
gptkbp:involves immunotherapy
autoimmunity
male infertility
gptkbp:locatedOnChromosome gptkb:X_chromosome
gptkbp:OMIM 300003
gptkbp:orthologIn gptkb:mouse
right
other mammals
gptkbp:proteinFamily MAGE homology domain
gptkbp:relatedTo apoptosis
DNA repair
cell cycle regulation
antigen processing
cancer-testis antigens
gptkbp:subfamily MAGE-A
MAGE-B
MAGE-C
MAGE-D
MAGE-E
MAGE-F
MAGE-G
MAGE-H
MAGE-L
MAGE-R
gptkbp:UniProtID Q13064
gptkbp:bfsParent gptkb:cancer/testis_antigen_family
gptkbp:bfsLayer 7