Lysosomes

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf Organelle
gptkbp:contains gptkb:Phosphatases
Proteases
Acid hydrolases
Cathepsins
Glycosidases
Hydrolytic enzymes
Lipases
Lysosomal membrane proteins
Lysosomal-associated membrane protein 1 (LAMP1)
Lysosomal-associated membrane protein 2 (LAMP2)
Mannose-6-phosphate receptors
Nucleases
Phospholipases
Sulfatases
gptkbp:discoveredBy gptkb:Christian_de_Duve
gptkbp:discoveredIn 1955
gptkbp:foundIn gptkb:Eukaryotic_cells
gptkbp:function Autophagy
Apoptosis
Breakdown of waste materials
Intracellular digestion
Destruction of cellular debris
https://www.w3.org/2000/01/rdf-schema#label Lysosomes
gptkbp:involvedIn Phagocytosis
Cellular homeostasis
Endocytosis
Lysosomal storage diseases
gptkbp:malfunctionCauses gptkb:Gaucher's_disease
gptkb:Tay-Sachs_disease
gptkb:Niemann-Pick_disease
gptkb:Fabry_disease
gptkb:Hurler_syndrome
gptkb:Pompe_disease
gptkb:Hunter_syndrome
gptkb:Metachromatic_leukodystrophy
I-cell disease
Mucolipidosis
gptkbp:membraneBound true
gptkbp:originatedIn gptkb:Golgi_apparatus
gptkbp:pH Acidic
gptkbp:presentIn Animal cells
gptkbp:rareIn Plant cells
gptkbp:regulates Cellular metabolism
gptkbp:relatedTo Autophagosomes
Endosomes
Peroxisomes
gptkbp:shape Spherical
gptkbp:size 0.1–1.2 μm
gptkbp:bfsParent gptkb:Platelet
gptkbp:bfsLayer 5