Statements (51)
Predicate | Object |
---|---|
gptkbp:instanceOf |
Organelle
|
gptkbp:contains |
gptkb:Phosphatases
Proteases Acid hydrolases Cathepsins Glycosidases Hydrolytic enzymes Lipases Lysosomal membrane proteins Lysosomal-associated membrane protein 1 (LAMP1) Lysosomal-associated membrane protein 2 (LAMP2) Mannose-6-phosphate receptors Nucleases Phospholipases Sulfatases |
gptkbp:discoveredBy |
gptkb:Christian_de_Duve
|
gptkbp:discoveredIn |
1955
|
gptkbp:foundIn |
gptkb:Eukaryotic_cells
|
gptkbp:function |
Autophagy
Apoptosis Breakdown of waste materials Intracellular digestion Destruction of cellular debris |
https://www.w3.org/2000/01/rdf-schema#label |
Lysosomes
|
gptkbp:involvedIn |
Phagocytosis
Cellular homeostasis Endocytosis Lysosomal storage diseases |
gptkbp:malfunctionCauses |
gptkb:Gaucher's_disease
gptkb:Tay-Sachs_disease gptkb:Niemann-Pick_disease gptkb:Fabry_disease gptkb:Hurler_syndrome gptkb:Pompe_disease gptkb:Hunter_syndrome gptkb:Metachromatic_leukodystrophy I-cell disease Mucolipidosis |
gptkbp:membraneBound |
true
|
gptkbp:originatedIn |
gptkb:Golgi_apparatus
|
gptkbp:pH |
Acidic
|
gptkbp:presentIn |
Animal cells
|
gptkbp:rareIn |
Plant cells
|
gptkbp:regulates |
Cellular metabolism
|
gptkbp:relatedTo |
Autophagosomes
Endosomes Peroxisomes |
gptkbp:shape |
Spherical
|
gptkbp:size |
0.1–1.2 μm
|
gptkbp:bfsParent |
gptkb:Platelet
|
gptkbp:bfsLayer |
5
|