Long-term evolution experiment

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf scientific research
gptkbp:availableOn publicly available
gptkbp:dailyTransfer 1% to fresh medium
gptkbp:fundedBy gptkb:National_Institutes_of_Health
gptkb:National_Science_Foundation
gptkbp:generationTime approximately 6.6 generations per day
gptkbp:goal study evolution in real time
https://www.w3.org/2000/01/rdf-schema#label Long-term evolution experiment
gptkbp:launched gptkb:Richard_Lenski
gptkbp:location gptkb:Michigan_State_University
gptkbp:medium glucose-limited minimal medium
gptkbp:notableAchievement evolution of cell size
evolution of compensatory mutations
evolution of ecological interactions
evolution of genetic robustness
evolution of growth rate
evolution of mutator phenotypes
evolution of pleiotropy
evolution of population dynamics
evolution of stress resistance
parallel evolution observed
clonal interference
evolution of DNA repair mechanisms
evolution of adaptation to novel environments
evolution of antibiotic resistance
evolution of epistasis
evolution of fitness relative to ancestor
evolution of gene regulation
evolution of genetic diversity
evolution of genome size
evolution of metabolic traits
evolution of parallel and convergent evolution
evolutionary contingency
genetic drift effects
mutation rate evolution
trade-offs in adaptation
gptkbp:notableFinds evolution of citrate utilization
genomic changes
increased fitness
gptkbp:numberOfPopulations 12
gptkbp:organism gptkb:Bacteria
gptkbp:publishedIn Blount, Z. D. et al. (2008) PNAS
Lenski, R. E. et al. (1991) Science
gptkbp:relatedTo E. coli long-term evolution project
gptkbp:startDate February 24, 1988
gptkbp:storage frozen samples at regular intervals
gptkbp:totalGenerations over 75,000
gptkbp:website https://lenski.mmg.msu.edu/ltee/
gptkbp:bfsParent gptkb:Richard_E._Lenski
gptkb:Robert_W._Lenski
gptkbp:bfsLayer 7